Friday, September 20, 2013

Love potion


No they didn’t found the love potion yet… but they are quiet close. An article entitled “Gene switches make prairie voles fall in love” in Nature caught my eye the other night. A study on certain specie of rodents (prairie voles) proved the involvement of epigenetics in love. These rodents are monogamous in nature and cohabit for a few hours before mating. The mating process triggers a chemical reaction in their brain making them more attached and loyal to one another. Here is what happens. DNA is a negatively charged molecule and is packed in the nucleus using a positively charged molecule called histone. To increase the expression of a certain gene, histone is acetylated, making it less positive and unwinds from DNA, increasing genetic expression. This what mating triggers in these rodents. It increases the expression of the receptors of vasopressin and oxytocin, two hormones known in their involvement in enhancing the feeling of closeness and attachment to another person in human beings.  A drug called trichostatin A was injected in the brain of the rodents and triggered a similar chemical reaction. The drug is a histone deacetylase inhibitor. It prevents the removal of acetyl groups from the DNA, hence enhancing the expression of the hormones. So a drug can induce the feeling of attachment and loyalty towards the partner. Did we find the ultimate love potion? Unfortunately no. The drug only works after cohabitation has occurred for several hours before. It only replaced mating as the trigger. So seduction and flirting are still a must.

2 comments:

  1. Well if only this could just cut out flirting. :) Is this kind of like the idea that the chemicals in chocolate that gives you a sense of love or feeling in love? I know in chocolate it does not make a person fall in love but the chemicals help trigger the feeling.

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  2. So I guess you can say we still need Cupid?! :)

    This topic is still interesting though. I love the idea that the pleasure of mating or falling in love is satisfied by the drug. Sooner or later, there will be pills that do the same thing sold in stores, only if people's ethics and morals do not stand in the way.

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